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发表时间:2013-12-17 13:22

An 8-year-old boy was admitted to our hospital due to intermittent episodes of dysphagia over the past 5 years, which was severely affecting his physical growth and quality of life. He was diagnosed as having achalasia 3 years ago, and had twice undergone endoscopic balloon...

发表时间:2013-12-11 14:05

Human dachshund homolog 1 (DACH1) is a major component of the Retinal Determination Gene Network (RDGN) and functions as a tumor suppressor. However, the regulation of DACH1 expression and its function in hepatocellular carcinoma (HCC) remain unclear. In this study, epigenetic changes...

发表时间:2013-10-18 13:20

Persistent infection with Helicobacter pylori (H. pylori) contributes to gastric diseases including chronic gastritis and gastric cancer. However, the pathogenesis of this carcinogenic bacterium has not been completely elucidated. Here, we report that H. pylori rapidly triggers STAT3 signaling and induces STAT3-dependent COX-2 expression both...

发表时间:2013-04-18 09:33

Epidermal growth factor receptor (EGFR) plays an important role in tumorigenesis of colorectal cancer (CRC), and its in vivo molecular imaging in rodent models has become the subject of an increased number of studies using novel imaging techniques for gastrointestinal endoscopy. Current study aimed to...